SCHEMBL3684844

SCHEMBL3684844

CC(O)CSSCC(C)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36
LMNA P02545 2/20 0.36
GMNN O75496 1/20 0.35
MAPT P10636 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3686166 0.86 TSHR (0.39) TSHRTDP1ALDH1A1LMNA
SCHEMBL3684334 0.86 TSHR (0.39) TSHRTDP1ALDH1A1LMNA
SCHEMBL10066792 0.83 TDP1 (0.45) TSHRTDP1ALDH1A1LMNA
SCHEMBL6025402 0.79
SCHEMBL2350785 0.77
SCHEMBL12315009 0.77
SCHEMBL13627864 0.77
SCHEMBL4730355 0.77
SCHEMBL10798332 0.74 TDP1 (0.43) TSHRTDP1
SCHEMBL29098228 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119318667-A Preparation and application of amphiphilic polymer prodrug loaded with nonsteroidal anti-inflammatory drug and platinum drug 中国石油化工股份有限公司 2025-01-17 CN claimed
CN-116333285-A Low-reactivity polyester polyol and preparation method and application thereof 万华化学集团股份有限公司 2023-06-27 CN claimed
US-5709737-A AQUEOUS LIQUID VEHICLE, COLORANT, ALCOHOL ADDITIVE; SUITABLE FOR MICROWAVE DRYING PROCESSES XEROX CORPORATION (US) 1998-01-20 US claimed
CN-119318667-A Preparation and application of amphiphilic polymer prodrug loaded with nonsteroidal anti-inflammatory drug and platinum drug 中国石油化工股份有限公司 2025-01-17 CN disclosed
CN-116333285-A Low-reactivity polyester polyol and preparation method and application thereof 万华化学集团股份有限公司 2023-06-27 CN disclosed
US-11246877-B2 Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof THE UNIVERSITY OF CHICAGO (US) 2022-02-15 US disclosed
US-20190269706-A1 NANOPARTICLES FOR CHEMOTHERAPY, TARGETED THERAPY, PHOTODYNAMIC THERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF THE UNIVERSITY OF CHICAGO 2019-09-05 US disclosed
EP-3439666-A1 NANOPARTICLES FOR CHEMOTHERAPY, TARGETED THERAPY, PHOTODYNAMIC THERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF The University of Chicago (US) 2019-02-13 EP disclosed
WO-2017201528-A1 NANOPARTICLES FOR CHEMOTHERAPY, TARGETED THERAPY, PHOTODYNAMIC THERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF THE UNIVERSITY OF CHICAGO (US) 2017-11-23 WO disclosed
EP-3211017-A1 POLYURETHANE Compagnie Générale des Etablissements Michelin (FR) 2017-08-30 EP disclosed
EP-2115033-B1 POLYURETHANE MICHELIN & CIE (FR) 2017-05-17 EP disclosed
US-4666618-A ANTIWEAR AND EXTREME PRESSURE ADDITIVES IN LUBRICANTS OR HYDRAULIC FLUIDS BAYER AKTIENGESELLSCHAFT (DE) 1987-05-19 US disclosed
EP-0205846-A1 Process for the preparation of low molecular weight hydroxy-functional (meth)acrylpolymers, their use in the preparation of prepolymers with isocyanate end groups and elastic sealants and adhesives prepared from these polymers Teroson GmbH (DE) 1986-12-30 EP disclosed
US-4589993-A Power transmission shift fluids containing two-component friction modifier additive EXXON RESEARCH & ENGINEERING CO. (US) 1986-05-20 US disclosed
EP-0113199-A2 Power transmission shift fluids containing two-component friction modifier additive EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-07-11 EP disclosed
US-4382002-A Drilling fluids containing an additive composition EXXON RESEARCH & ENGINEERING CO. (US) 1983-05-03 US disclosed
EP-0068601-A1 Drilling fluids containing an additive composition EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-05 EP disclosed
US-4344853-A AUTOMATIC TRANSMISSION FLUIDS EXXON RESEARCH & ENGINEERING CO. (US) 1982-08-17 US disclosed
US-4322214-A USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING ASAHI CHEMICAL COMPANY LIMITED (JP) 1982-03-30 US disclosed
US-3952063-A Process for the preparation of an organomercaptophenol from sulfur, a phenol, and an activated olefin or an epoxy compound GENERAL ELECTRIC COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190269706-A1 NANOPARTICLES FOR CHEMOTHERAPY, TARGETED THERAPY, PHOTODYNAMIC THERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF CD274, PDCD1, PDCD1LG2 TSHR 3605/4885TDP1 3263/4885ALDH1A1 460/4885
US-11246877-B2 Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof CD274, PDCD1, PDCD1LG2 TSHR 3605/4885TDP1 3263/4885ALDH1A1 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.