SCHEMBL3684945

SCHEMBL3684945

c1ccc(-c2ncc[nH]2)c(-c2cscn2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.49
METAP1 P53582 5/20 0.45
METAP2 P50579 5/20 0.45
CSNK1A1 P48729 1/20 0.45
TYRO3 Q06418 1/20 0.45
DYRK1B Q9Y463 1/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
RAB9A P51151 1/20 0.45
FKBP1A P62942 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HIF1A Q16665 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6179554 0.81 METAP1 (0.46) F2RL1METAP1METAP2KDM4ENPC1
SCHEMBL9622149 0.81 F2RL1 (0.42) F2RL1METAP1METAP2CSNK1A1TYRO3
SCHEMBL9287236 0.80 NISCH (0.64) F2RL1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL14886257 0.78 NISCH (0.61) F2RL1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL27536698 0.74 CSNK1A1 (0.45) F2RL1CSNK1A1TYRO3DYRK1BKDM4E
SCHEMBL26259959 0.73 METAP2 (0.44) F2RL1METAP1METAP2KDM4ENPC1
SCHEMBL30222222 0.72 NISCH (0.53) CSNK1A1TYRO3DYRK1BKDM4ETDP1
SCHEMBL1369295 0.72 NISCH (0.53) CSNK1A1TYRO3DYRK1BKDM4ETDP1
SCHEMBL471923 0.72 NISCH (0.70) CSNK1A1TYRO3DYRK1BKDM4ECYP1A2
SCHEMBL26259955 0.70 NISCH (0.61) CSNK1A1TYRO3DYRK1BKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0366009-A1 Fungicide for the protection of plants BASF Aktiengesellschaft (DE) 1990-05-02 EP claimed
EP-0257828-A1 Dipropargyloxybenzene compounds and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-02 EP claimed
EP-0217579-A1 Fungicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-04-08 EP claimed
EP-0093620-B1 FUNGICIDAL N-PHENYLCARBAMATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-01-07 EP claimed
JP-59102933-A None JP disclosed
JP-4103647-A None JP disclosed
JP-6298615-A None JP disclosed
US-7723418-B2 Antistatic resin composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2010-05-25 US disclosed
US-7144451-B2 Printing sheet-form substrates by the inkjet printing with an aqueous ink CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-12-05 US disclosed
US-20050049360-A1 Mixture of thermoplastic resin and antistatic agents; polyamideesterether block polymers SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-03-03 US disclosed
EP-1343849-A2 METHOD OF PRINTING SHEET-FORM SUBSTRATES BY THE INKJET PRINTING PROCESS Ciba SC Holding AG (CH) 2003-09-17 EP disclosed
WO-2002050196-A2 METHOD OF PRINTING SHEET-FORM SUBSTRATES BY THE INKJET PRINTING PROCESS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-06-27 WO disclosed
US-4946865-A FUNGICIDES; APPLYING TO PLANT PATHOGENIC FUNGI WHICH ARE RESISTANT TO BENZIMIDAZOLE OR THIOPHANATE FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-08-07 US disclosed
US-4870064-A PHYTOPATHOGEN FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-09-26 US disclosed
US-4752615-A USEFUL ON BENZIMIDHZOLE, THIOPHANATE, AND CYCLIC IMIDE RESISTANT FUNGI SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-21 US disclosed
US-4710514-A Fungicidal carbamates and thiolcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-01 US disclosed
US-4647583-A Fungicidal aniline derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-03-03 US disclosed
US-4608385-A EFFECTIVE AGAINST RESISTANT STRAINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-26 US disclosed
US-4482546-A Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-13 US disclosed
JP-S59102933-A SPONGE RUBBER COMPOSITION KANEBO LTD 1984-06-14 JP disclosed