Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241791 | 0.78 | NPSR1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL29363525 | 0.78 | NPSR1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL25329603 | 0.71 | MCHR1 (0.39) | MAPTHTTLMNAALOX12NPSR1 | |
| Sulfuric Acid SCHEMBL2315182 | 0.70 | NPSR1 (0.43) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| Chlorothalonil SCHEMBL8995729 | 0.70 | NPSR1 (0.39) | MEN1CYP3A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12612965 | 0.70 | NPSR1 (0.53) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8061442 | 0.69 | CYP2C9 (0.44) | MEN1KMT2ACYP2C9CYP2C19NPSR1 | |
| SCHEMBL10816110 | 0.68 | SMN1; SMN2 (0.68) | KMT2AMAPTSMN1; SMN2LMNACYP2C9 | |
| SCHEMBL3599554 | 0.67 | GAA (0.44) | SMN1; SMN2HTTNPSR1TSHRGAA | |
| SCHEMBL8070357 | 0.66 | NPSR1 (0.43) | MAPTSMN1; SMN2LMNANPSR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1876897-B1 | ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2010-09-29 | — | — | EP | disclosed |
| EP-1696727-B1 | SYNERGISTIC INSECTICIDAL MIXTURES | BAYER CROPSCIENCE AG (DE) | 2009-04-08 | — | — | EP | disclosed |