Chlorothalonil

Chlorothalonil

SCHEMBL8995729

CSc1nc(NC2CC2)nc(NC(C)(C)C)n1.N#Cc1c(Cl)c(Cl)c(Cl)c(C#N)c1Cl

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.39
PDE4A P27815 5/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
TSHR P16473 2/20 0.32
HTT P42858 2/20 0.32
GLA P06280 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 2/20 0.32
GAA P10253 1/20 0.31
CTSV O60911 1/20 0.31
PLAT P00750 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363525 0.83 NPSR1 (0.50) NPSR1PDE4ASMN1; SMN2LMNAKMT2A
SCHEMBL241791 0.83 NPSR1 (0.50) NPSR1PDE4ASMN1; SMN2LMNAKMT2A
Sulfuric Acid SCHEMBL2315182 0.75 NPSR1 (0.43) NPSR1PDE4ASMN1; SMN2LMNAKMT2A
SCHEMBL8061442 0.73 CYP2C9 (0.44) NPSR1PDE4AKMT2AMEN1CYP1A2
SCHEMBL10816110 0.72 SMN1; SMN2 (0.68) NPSR1PDE4ASMN1; SMN2LMNAKMT2A
SCHEMBL8061703 0.70 MEN1 (0.44) NPSR1PDE4ASMN1; SMN2LMNAKMT2A
SCHEMBL8061638 0.70 LMNA (0.54) PDE4ASMN1; SMN2LMNAKMT2AMEN1
Dichlorophen SCHEMBL3685255 0.70 HIF1A (0.41) NPSR1PDE4ASMN1; SMN2LMNAKMT2A
SCHEMBL19470805 0.70 NPSR1 (0.36) NPSR1PDE4AKMT2AMEN1CYP1A2
SCHEMBL11254860 0.69 PDE4A (0.51) PDE4AKMT2AMEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5507862-A PROTECTIVE COATINGS CONTAINING SUBSTITUTED N-PHENYLISOTHIAZOLONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-16 US disclosed