Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 11/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26819803 | 0.89 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| SCHEMBL26819807 | 0.85 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| SCHEMBL12450000 | 0.85 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| SCHEMBL13624112 | 0.84 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| SCHEMBL26819793 | 0.84 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| SCHEMBL17673749 | 0.84 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| SCHEMBL19318761 | 0.84 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| SCHEMBL26819797 | 0.84 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| Water SCHEMBL27701299 | 0.83 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 | |
| SCHEMBL16881172 | 0.82 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1TNK2NR1H2PIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845317-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160376260-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2016-12-29 | — | — | US | disclosed |
| US-9328102-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150246905-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | NATIONAL SCIENCE FOUNDATION | 2015-09-03 | — | — | US | disclosed |
| US-9006463-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-14 | — | — | US | disclosed |
| US-20130317223-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-11-28 | — | — | US | disclosed |
| US-8338601-B2 | Slow release of organoboronic acids in cross-coupling reactions | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100121062-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246905-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | HSP90AA1 4149/4885HSP90AB1 3408/4885TNK2 1943/4885 |
| US-20100121062-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | HSP90AA1 4149/4885HSP90AB1 3408/4885TNK2 1943/4885 |
| US-20160376260-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | HSP90AA1 4149/4885HSP90AB1 3408/4885TNK2 1943/4885 |
| US-20130317223-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | HSP90AA1 4149/4885HSP90AB1 3408/4885TNK2 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.