Citral

Citral

SCHEMBL3685903

CC(C)=CCC/C(C)=C/C=O.CCCC(=O)/C=C/C=C(\C)CCC=C(C)C.CCCC(C)=O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
NR1I2 O75469 1/20 0.49
LMNA P02545 1/20 0.49
PGR P06401 1/20 0.49
FNTA P49354 2/20 0.44
FNTB P49356 2/20 0.44
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
POLB P06746 1/20 0.41
TRPA1 O75762 1/20 0.37
KMT2A Q03164 2/20 0.36
ALOX15 P16050 2/20 0.36
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citral SCHEMBL3685905 1.00 ALDH1A1 (0.58) ALDH1A1NR1I2LMNAPGRFNTA
SCHEMBL1275716 0.90 NR1I2 (0.59) ALDH1A1NR1I2LMNAPGRFNTA
SCHEMBL1275719 0.90 NR1I2 (0.59) ALDH1A1NR1I2LMNAPGRFNTA
Citral SCHEMBL3684832 0.79 ALDH1A1 (0.70) ALDH1A1NR1I2LMNAPGRFNTA
SCHEMBL2861207 0.79 NR1I2 (0.61) ALDH1A1NR1I2LMNAPGRFNTA
SCHEMBL2861204 0.79 NR1I2 (0.61) ALDH1A1NR1I2LMNAPGRFNTA
Citral SCHEMBL357176 0.78 ALDH1A1 (0.88) ALDH1A1NR1I2LMNAPGRFNTA
Citral SCHEMBL31138003 0.77 ALDH1A1 (0.72) ALDH1A1NR1I2LMNAPGRFNTA
Citral SCHEMBL17652423 0.77 ALDH1A1 (0.78) ALDH1A1NR1I2LMNAPGRFNTA
Citral SCHEMBL2473483 0.77 ALDH1A1 (0.91) ALDH1A1NR1I2LMNAPGRFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150516-A1 ALDOL CONDENSATION REACTION AND CATALYST THEREFORE DSM IP Assets B.V. (NL) 2010-02-10 EP disclosed
EP-2134670-A1 NOVEL PROCESS FOR THE PREPARATION OF TIMBERONE DSM IP Assets B.V. (NL) 2009-12-23 EP disclosed
WO-2008145350-A1 ALDOL CONDENSATION REACTION AND CATALYST THEREFORE DSM IP ASSETS B.V. (NL) 2008-12-04 WO disclosed
WO-2008113545-A1 NOVEL PROCESS FOR THE PREPARATION OF TIMBERONE DSM IP ASSETS B.V. (NL) 2008-09-25 WO disclosed