Sulfuric Acid

Sulfuric Acid

SCHEMBL3686178

CCC[P+](CCC)(CCC)CCC.O=S(=O)([O-])O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CYP51cyp51Acyp51c

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42
TP53 P04637 2/20 0.39
CYP3A4 P08684 2/20 0.35
NFKB1 P19838 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
DNM1 Q05193 2/20 0.32
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL11533305 0.87 DNM1 (0.56) TSHRTP53DNM1CES2CES1
Sulfuric Acid SCHEMBL3686176 0.86 TP53 (0.41) TSHRTP53CYP3A4NFKB1NPSR1
SCHEMBL7134478 0.86 TP53 (0.35) TSHRTP53CYP3A4NFKB1NPSR1
Sulfuric Acid SCHEMBL3343165 0.84 DNM1 (0.52) TSHRMEN1ALDH1A1KMT2ATP53
Sulfuric Acid SCHEMBL23089049 0.80 DNM1 (0.61) TSHRTP53DNM1CES2CES1
Sulfuric Acid SCHEMBL7558714 0.80 DNM1 (0.61) TSHRTP53DNM1CES2CES1
Sulfuric Acid SCHEMBL7175402 0.80 DNM1 (0.61) TSHRTP53DNM1CES2CES1
Sulfuric Acid SCHEMBL11127001 0.80 DNM1 (0.61) TSHRTP53DNM1CES2CES1
Sulfuric Acid SCHEMBL28580443 0.79 DNM1 (0.65) TSHRTP53DNM1CES2CES1
Sulfuric Acid SCHEMBL10529623 0.79 DNM1 (0.65) TSHRTP53DNM1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100036029-A1 POLYMER-(ORGANO)CLAY COMPOSITE, COMPOSITION COMPRISING THE COMPOSITE, SHEET-LIKE MATERIAL COMPRISING THE COMPOSITE OR THE COMPOSITION, AND PROCESS FOR PRODUCTION OF POLYMER-(ORGANO)CLAY COMPOSITE ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-02-11 US disclosed
EP-2113526-A1 POLYMER-(ORGANO)CLAY COMPLEX, COMPOSITION COMPRISING THE COMPLEX, SHEET-LIKE MATERIAL COMPRISING THE COMPLEX OR COMPOSITION, AND METHOD FOR PRODUCTION OF POLYMER-(ORGANO)CLAY COMPLEX Asahi Kasei Chemicals Corporation (JP) 2009-11-04 EP disclosed
EP-1275694-A1 AROMATIC POLYCARBONATE COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2003-01-15 EP disclosed
US-4658041-A EQUILIBRIUM INTERCHANGE OF ALKYL HALIDES AND AN ALKYL CARBONATE USING A BASIC CATALYST THE DOW CHEMICAL COMPANY (US) 1987-04-14 US disclosed
US-4656284-A BASIC CATALYST OR QUATERNARY SALT INITIATOR THE DOW CHEMICAL COMPANY (US) 1987-04-07 US disclosed
US-4642349-A REACTING AROMATIC CARBONATE AND ORGANIC HALIDE THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed
US-4612386-A Process for making esters THE DOW CHEMICAL COMPANY (US) 1986-09-16 US disclosed
EP-0060904-B1 A PROCESS FOR MAKING VICINAL EPOXIDES AND ALKYL HALIDES OR ALKYLENE DIHALIDES FROM CARBONATE ESTERS THE DOW CHEMICAL COMPANY (US) 1986-09-10 EP disclosed
US-4595763-A Contacting aromatic hydroxyl- or thiol-containing compound with methyl trichloroacetate in the presence of a catalytic amount of initiator THE DOW CHEMICAL COMPANY (US) 1986-06-17 US disclosed
US-4584408-A Preparation of 1,3-bis(aryloxy)-2-propanols THE DOW CHEMICAL COMPANY (US) 1986-04-22 US disclosed
US-4410718-A CARBOXYLIC ACID, TRICHLOROACETATE THE DOW CHEMICAL COMPANY (US) 1983-10-18 US disclosed
US-4380636-A ESTERIFICATION, CATALYSTS THE DOW CHEMICAL COMPANY (US) 1983-04-19 US disclosed
US-4375549-A FROM ORGANIC SILYL HALIDE AND A CARBONATE THE DOW CHEMICAL COMPANY (US) 1983-03-01 US disclosed
US-4375548-A CONDENSATION OF A SILYLATED TRICHLOROACETATE WITH AN ALDEHYDE OR KETONE, WITH AN INITIATOR THE DOW CHEMICAL COMPANY (US) 1983-03-01 US disclosed
US-4360686-A WITH TRIMETHYLSILYL TRICHLOROACETATE WITH ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1982-11-23 US disclosed
EP-0060904-A1 A process for making vicinal epoxides and alkyl halides or alkylene dihalides from carbonate esters THE DOW CHEMICAL COMPANY (US) 1982-09-29 EP disclosed
US-4349487-A METHYL TRICHLOROACETATE, PRIMARY ALKYL HALIDE OR AROMATIC HALIDE WITH ELECTRON-WITHDRAWING GROUP, CATALYST THE DOW CHEMICAL COMPANY (US) 1982-09-14 US disclosed
US-4349482-A Process for making vicinal epoxides and dihalides THE DOW CHEMICAL CO. (US) 1982-09-14 US disclosed
US-4336195-A Preparation of cyclic ethers THE DOW CHEMICAL COMPANY (US) 1982-06-22 US disclosed
US-4261906-A DECOMPOSITION OF BETA-HALOALKYL CARBONATE IN PRESENCE OF QUATERNARY AMMONIUM OR PHOSPHONIUM SALT THE DOW CHEMICAL COMPANY (US) 1981-04-14 US disclosed