Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909196 | 0.85 | GGPS1 (0.55) | GGPS1FDPSGPR84NPC1RAB9A | |
| SCHEMBL17519485 | 0.84 | GGPS1 (0.54) | GGPS1FDPSGPR84NPC1RAB9A | |
| SCHEMBL633944 | 0.84 | GGPS1 (0.57) | GGPS1FDPSGPR84NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9121777 | 0.84 | GGPS1 (0.54) | GGPS1FDPSGPR84NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8661446 | 0.84 | GGPS1 (0.54) | GGPS1FDPSGPR84NPC1RAB9A | |
| SCHEMBL28284831 | 0.83 | GGPS1 (0.52) | GGPS1FDPSGPR84NPC1RAB9A | |
| SCHEMBL1761303 | 0.80 | GGPS1 (0.53) | GGPS1FDPSGPR84NPC1RAB9A | |
| SCHEMBL20434857 | 0.80 | GGPS1 (0.50) | GGPS1FDPSGPR84NPC1RAB9A | |
| Beta-Alanine SCHEMBL4783165 | 0.78 | GGPS1 (0.48) | GGPS1FDPSGPR84NPC1RAB9A | |
| SCHEMBL21076445 | 0.78 | GGPS1 (0.48) | GGPS1FDPSGPR84NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170882-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | Gilead Colorado, Inc. (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009002534-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | GILEAD COLORADO, INC. (US) | 2008-12-31 | — | — | WO | disclosed |