Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909196 | 0.91 | GGPS1 (0.55) | GGPS1FDPSGPR84ERCC5PTGS1 | |
| Hydrochloric Acid SCHEMBL9121777 | 0.90 | GGPS1 (0.54) | GGPS1FDPSGPR84ERCC5PTGS1 | |
| Hydrochloric Acid SCHEMBL8661446 | 0.90 | GGPS1 (0.54) | GGPS1FDPSGPR84ERCC5PTGS1 | |
| SCHEMBL7961082 | 0.82 | GGPS1 (0.52) | GGPS1FDPSGPR84ERCC5PTGS1 | |
| SCHEMBL633944 | 0.81 | GGPS1 (0.57) | GGPS1FDPSGPR84ERCC5PTGS1 | |
| SCHEMBL3686302 | 0.78 | GGPS1 (0.54) | GGPS1FDPSGPR84ERCC5ALDH1A1 | |
| SCHEMBL17519485 | 0.78 | GGPS1 (0.54) | GGPS1FDPSGPR84ERCC5ALDH1A1 | |
| SCHEMBL1761303 | 0.77 | GGPS1 (0.53) | GGPS1FDPSGPR84ERCC5ALDH1A1 | |
| SCHEMBL28284831 | 0.77 | GGPS1 (0.52) | GGPS1FDPSGPR84ERCC5ALDH1A1 | |
| SCHEMBL3796430 | 0.76 | GGPS1 (0.50) | GGPS1FDPSGPR84ERCC5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035131-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BISPHOSPHONIC ACID | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |