Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.54 |
| ▸ | FNTA | P49354 | 15/20 | 0.47 |
| ▸ | FNTB | P49356 | 15/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 15/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501097 | 0.81 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| SCHEMBL88059 | 0.72 | CYP19A1 (1.00) | CYP19A1FNTAFNTBPGGT1BCYP11B1 | |
| Hydrochloric Acid SCHEMBL1507826 | 0.71 | CYP19A1 (0.97) | CYP19A1FNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL3502730 | 0.65 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| Acetic Acid SCHEMBL2789778 | 0.65 | CYP19A1 (0.81) | CYP19A1FNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL7841243 | 0.65 | CYP19A1 (0.68) | CYP19A1FNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL3686703 | 0.65 | FNTA (0.33) | FNTAFNTBPGGT1B | |
| SCHEMBL3501696 | 0.64 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL29361477 | 0.64 | AHR (0.50) | — | |
| SCHEMBL1420318 | 0.64 | AHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057028-A9 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010057028-A2 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |