Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686705 | 0.65 | CYP19A1 (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL3501097 | 0.64 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| SCHEMBL4209359 | 0.57 | BCHE (0.44) | BCHE | |
| SCHEMBL1668722 | 0.56 | CYP19A1 (0.41) | — | |
| SCHEMBL5008733 | 0.55 | BCHE (0.45) | BCHE | |
| SCHEMBL27261747 | 0.53 | CYP11B1 (0.39) | TBXAS1 | |
| SCHEMBL2261191 | 0.53 | AHR (0.47) | — | |
| SCHEMBL12543495 | 0.53 | AHR (0.47) | BCHE | |
| SCHEMBL28355829 | 0.52 | CYP11B1 (0.41) | KMT2ATBXAS1 | |
| SCHEMBL8685340 | 0.52 | LMNA (0.67) | MEN1KMT2ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057028-A9 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010057028-A2 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |