Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 13/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369229 | 0.90 | PPARG (0.37) | S1PR3S1PR1POLBPPARGL3MBTL1 | |
| SCHEMBL369536 | 0.87 | POLB (0.38) | S1PR3S1PR1MDM2POLBL3MBTL1 | |
| SCHEMBL1390467 | 0.86 | POLB (0.37) | S1PR3S1PR1MDM2POLBL3MBTL1 | |
| SCHEMBL368098 | 0.86 | GCG (0.39) | S1PR3S1PR1MDM2POLBHPGD | |
| SCHEMBL368689 | 0.85 | MAPK14 (0.36) | S1PR3S1PR1MDM2BRD4 | |
| SCHEMBL1390322 | 0.85 | MAPK14 (0.36) | S1PR3S1PR1MDM2BRD4 | |
| SCHEMBL371366 | 0.85 | KMT2A (0.46) | S1PR3S1PR1MDM2POLBBRD4 | |
| SCHEMBL369928 | 0.84 | CYP2C9 (0.39) | S1PR3S1PR1MDM2POLBKMT2A | |
| SCHEMBL369981 | 0.83 | EPHX2 (0.38) | S1PR3S1PR1MDM2LMNA | |
| SCHEMBL370027 | 0.83 | EPHX2 (0.37) | S1PR3S1PR1POLBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |