Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368688 | 0.90 | S1PR3 (0.39) | PPARGPOLBL3MBTL1BRD4S1PR3 | |
| SCHEMBL369581 | 0.86 | POLB (0.40) | POLBPTGER4PTGDRCREBBPL3MBTL1 | |
| SCHEMBL371309 | 0.86 | POLB (0.40) | POLBCREBBPL3MBTL1BRD4MEN1 | |
| SCHEMBL368555 | 0.85 | GCG (0.37) | POLBCREBBPL3MBTL1BRD4MEN1 | |
| SCHEMBL1390515 | 0.85 | MAPK14 (0.35) | POLBCREBBPL3MBTL1BRD4MEN1 | |
| SCHEMBL369230 | 0.85 | MAPK14 (0.35) | POLBCREBBPL3MBTL1BRD4MEN1 | |
| SCHEMBL1390419 | 0.85 | LMNA (0.43) | POLBCREBBPL3MBTL1MEN1KMT2A | |
| SCHEMBL369750 | 0.85 | POLB (0.40) | POLBCREBBPL3MBTL1BRD4MEN1 | |
| SCHEMBL15832896 | 0.85 | POLB (0.39) | POLBCREBBPL3MBTL1BRD4MEN1 | |
| SCHEMBL368816 | 0.85 | KMT2A (0.46) | POLBCREBBPL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |