Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387872 | 0.97 | CES2 (0.39) | CES2CES1 | |
| Lithium Ion SCHEMBL1451693 | 0.94 | CES2 (0.38) | CES2CES1 | |
| SCHEMBL1451135 | 0.94 | CES2 (0.38) | CES2CES1 | |
| Potassium Ion SCHEMBL2056582 | 0.94 | CES2 (0.38) | CES2CES1 | |
| SCHEMBL1450793 | 0.94 | CES2 (0.38) | CES2CES1 | |
| Benzene SCHEMBL29856148 | 0.91 | CES2 (0.36) | CES2CES1 | |
| SCHEMBL19759479 | 0.82 | EGFR (0.33) | CES2CES1 | |
| SCHEMBL25994263 | 0.80 | CES2 (0.33) | CES2CES1 | |
| SCHEMBL30420615 | 0.80 | EGFR (0.32) | CES2CES1 | |
| SCHEMBL1078077 | 0.80 | CES2 (0.30) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671210-B2 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| EP-1783130-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-12-30 | — | — | EP | disclosed |
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1783130-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | CBR3, C9, CBR1 | CES2 108/4885CES1 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.