Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL3690236 | 0.98 | TRPV1 (0.39) | TRPV1CNR1CNR2USP2MEN1 | |
| Stearic Acid SCHEMBL3686276 | 0.98 | TRPV1 (0.39) | TRPV1CNR1CNR2USP2MEN1 | |
| Stearic Acid SCHEMBL3696710 | 0.98 | TRPV1 (0.39) | TRPV1CNR1CNR2USP2MEN1 | |
| Stearic Acid SCHEMBL3691439 | 0.98 | TRPV1 (0.39) | TRPV1CNR1CNR2USP2MEN1 | |
| SCHEMBL3690998 | 0.94 | NFKB1 (0.44) | TRPV1CNR1CNR2USP2KMT2A | |
| Potassium Ion SCHEMBL3689819 | 0.92 | NFKB1 (0.44) | TRPV1CNR1CNR2USP2KMT2A | |
| Zinc Ion SCHEMBL3689488 | 0.92 | NFKB1 (0.44) | TRPV1CNR1CNR2USP2KMT2A | |
| SCHEMBL3687278 | 0.92 | NFKB1 (0.47) | TRPV1CNR1CNR2USP2KMT2A | |
| SCHEMBL3692052 | 0.92 | NFKB1 (0.44) | TRPV1CNR1CNR2USP2KMT2A | |
| SCHEMBL2866093 | 0.83 | USP2 (0.53) | USP2MEN1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723413-B2 | Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-20070142514-A1 | Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-06-21 | — | — | US | disclosed |