⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309843 | 0.78 | — | — | |
| SCHEMBL18122745 | 0.76 | — | — | |
| SCHEMBL22650272 | 0.76 | — | — | |
| SCHEMBL9373386 | 0.71 | — | — | |
| SCHEMBL19155825 | 0.69 | COMT (0.32) | — | |
| SCHEMBL2125364 | 0.67 | — | — | |
| SCHEMBL25925862 | 0.66 | MAPT (0.34) | — | |
| SCHEMBL18673980 | 0.66 | NPC1 (0.31) | — | |
| SCHEMBL15950989 | 0.66 | COMT (0.60) | — | |
| SCHEMBL18698931 | 0.66 | KMT2A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623967-B2 | Polymers functionalized with nitroso compounds | BRIDGESTONE CORPORATION (JP) | 2014-01-07 | — | — | US | claimed |
| US-20130096264-A1 | POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-04-18 | — | — | US | claimed |
| US-8188195-B2 | Polymers functionalized with nitroso compounds | BRIDGESTONE CORPORATION (JP) | 2012-05-29 | — | — | US | claimed |
| US-20100168378-A1 | POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-07-01 | — | — | US | claimed |
| US-9670299-B2 | Polymers functionalized with nitroso compounds | BRIDGESTONE CORPORATION (JP) | 2017-06-06 | — | — | US | disclosed |
| US-20160032030-A1 | POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2016-02-04 | — | — | US | disclosed |
| US-9127100-B2 | Polymers functionalized with nitroso compounds | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20140100340-A1 | POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2014-04-10 | — | — | US | disclosed |
| US-8623967-B2 | Polymers functionalized with nitroso compounds | BRIDGESTONE CORPORATION (JP) | 2014-01-07 | — | — | US | disclosed |
| US-20130096264-A1 | POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-04-18 | — | — | US | disclosed |
| US-8188195-B2 | Polymers functionalized with nitroso compounds | BRIDGESTONE CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-20100168378-A1 | POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-07-01 | — | — | US | disclosed |