⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309843 | 0.73 | — | — | |
| SCHEMBL18122745 | 0.71 | — | — | |
| SCHEMBL3687318 | 0.71 | — | — | |
| SCHEMBL22650272 | 0.71 | — | — | |
| SCHEMBL27415489 | 0.67 | — | — | |
| SCHEMBL21597560 | 0.65 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL31454583 | 0.64 | HTT (0.45) | — | |
| SCHEMBL27415137 | 0.63 | — | — | |
| SCHEMBL15589312 | 0.62 | KDM4E (0.42) | — | |
| SCHEMBL27415135 | 0.62 | HPGD (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617786-B2 | Dihydro-cyclopenta-isoquinoline sulfonamides derivatives | UCB Biopharma SRL (BE) | 2026-05-05 | — | — | US | disclosed |
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| US-20240092773-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES | UCB Biopharma SRL (BE) | 2024-03-21 | — | — | US | disclosed |
| US-20220332709-A1 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2022-10-20 | — | — | US | disclosed |
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |
| EP-0249938-B1 | Imidazolesulfonamide derivatives, herbicides and a method for inhibiting growth of undesirable plants | NISSAN CHEMICAL IND LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-4830660-A | Imidazolesulfonamide derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0249938-A2 | Imidazolesulfonamide derivatives, herbicides and a method for inhibiting growth of undesirable plants | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-12-23 | — | — | EP | disclosed |