SCHEMBL3687476

SCHEMBL3687476

CN1C(=O)c2c(Br)c(Br)c(Br)c(Br)c2C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
CA9 Q16790 8/20 0.37
HIPK2 Q9H2X6 1/20 0.36
CA2 P00918 7/20 0.36
CA7 P43166 7/20 0.36
CA1 P00915 6/20 0.36
CA4 P22748 2/20 0.36
CA12 O43570 6/20 0.35
CASP3 P42574 3/20 0.35
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
CASP1 P29466 1/20 0.31
BRCA1 P38398 1/20 0.31
CASP7 P55210 1/20 0.31
KMT2A Q03164 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12869420 0.86 CASP3 (0.34) TSHRCA9CASP3MAPT
SCHEMBL19370217 0.81 CASP3 (0.33) CASP3
SCHEMBL14000267 0.79 CASP3 (0.32) CA9CASP3
SCHEMBL3683578 0.75 TSHR (0.43) TSHRCA9HIPK2CA2CA7
SCHEMBL29366486 0.74 CA9 (0.49) TSHRCA9HIPK2CA2CA7
SCHEMBL94242 0.74 CA9 (0.49) TSHRCA9HIPK2CA2CA7
SCHEMBL12869413 0.74 MEN1 (0.44) CASP3MAPTMEN1USP2CASP1
SCHEMBL17682019 0.73 CYP1B1 (0.41) CA9CA2CA7CA1CA4
SCHEMBL10933086 0.72 CA9 (0.44) TSHRCA9HIPK2CA2CA7
SCHEMBL12629769 0.72 CASP3 (0.33) CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152803-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2010-02-17 EP disclosed
US-20080303006-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSTION CITIBANK, N.A., AS COLLATERAL AGENT 2008-12-11 US disclosed
WO-2008149260-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (US) 2008-12-11 WO disclosed
US-7041781-B2 Thermoplastic molding compounds with improved surface properties and improved structural homogeneity BAYER AKTIENGESELLSCHAFT (DE) 2006-05-09 US disclosed
EP-1169386-B2 FLAME-RESISTANT THERMOPLASTIC MOULDING MATERIAL BAYER AG (DE) 2005-10-19 EP disclosed
EP-1290065-B1 THERMOPLASTIC MOLDING COMPOUNDS WITH IMPROVED SURFACE PROPERTIES AND IMPROVED STRUCTURAL HOMOGENEITY LANXESS DEUTSCHLAND GMBH (DE) 2005-08-31 EP disclosed
EP-1133529-B1 THERMOPLASTIC RESINS WITH A LOW PROPORTION OF COARSE PARTICLES BAYER AG (DE) 2005-07-06 EP disclosed
EP-1004620-B1 Thermoplastic moulding compositions containing magnesium-aluminum-silikates BAYER MATERIALSCIENCE AG (DE) 2005-03-09 EP disclosed
EP-1004619-B1 Thermoplastic moulding compositions containing magnesium-aluminum silicates BAYER MATERIALSCIENCE AG (DE) 2004-10-27 EP disclosed
US-6797784-B1 Thermoplastic resins with a low proportion of coarse particles BAYER AKTIENGESELLSCHAFT (DE) 2004-09-28 US disclosed
US-4481338-A POLYCARBONATE-POLYPHOSPHATE BLEND BAYER AKTIENGESELLSCHAFT (DE) 1984-11-06 US disclosed
US-4463130-A POLYCARBONATE, STYRENE POLYMER AND POLYPHOSPHATE POLYMER; MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1984-07-31 US disclosed
EP-0103230-A2 Flame-retardant polymer mixtures BAYER AG (DE) 1984-03-21 EP disclosed
EP-0086353-A1 Polycarbonate moulding compounds with flame resistance BAYER AG (DE) 1983-08-24 EP disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
EP-0042561-A1 Fire-proofed moulding masses based on aromatic thermoplastic polyesters, process for its preparation and use in the production of shaped articles BAYER AG (DE) 1981-12-30 EP disclosed
US-4268429-A Novel flame retardant polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1981-05-19 US disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed
US-4024102-A Molding composition suitable for forming improved flame retardant three-dimensional shaped articles CELANESE CORPORATION (US) 1977-05-17 US disclosed
US-3943199-A Brominated aromatic polyphosphate copolymers CELANESE CORPORATION (US) 1976-03-09 US disclosed