Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | CPT2 | P23786 | 3/20 | 0.34 |
| ▸ | CPT1A | P50416 | 3/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3687516 | 1.00 | S1PR2 (0.37) | S1PR2S1PR1S1PR4S1PR3CPT2 | |
| SCHEMBL13410033 | 0.93 | S1PR1 (0.42) | S1PR2S1PR1S1PR4S1PR3ACACB | |
| SCHEMBL3686893 | 0.89 | CPT2 (0.45) | CPT2CPT1ACPT1B | |
| SCHEMBL3686891 | 0.89 | CPT2 (0.45) | CPT2CPT1ACPT1B | |
| Trifluoroacetic Acid SCHEMBL3685224 | 0.87 | CPT2 (0.34) | S1PR2S1PR1S1PR4S1PR3CPT2 | |
| Trifluoroacetic Acid SCHEMBL3685221 | 0.87 | CPT2 (0.34) | S1PR2S1PR1S1PR4S1PR3CPT2 | |
| SCHEMBL3687517 | 0.86 | ACACB (0.35) | S1PR1S1PR4S1PR3CPT2CPT1A | |
| Trifluoroacetic Acid SCHEMBL3682670 | 0.85 | S1PR1 (0.40) | S1PR2S1PR1S1PR4S1PR3CPT2 | |
| Trifluoroacetic Acid SCHEMBL3682673 | 0.85 | S1PR1 (0.40) | S1PR2S1PR1S1PR4S1PR3CPT2 | |
| Trifluoroacetic Acid SCHEMBL3683485 | 0.84 | MMP2 (0.41) | S1PR2S1PR1S1PR4S1PR3CPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | S1PR2 413/4885S1PR1 400/4885S1PR4 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.