SCHEMBL3687641

SCHEMBL3687641

CCC(O)CCNCc1ccncc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42
SLC2A4 P14672 1/20 0.41
GAA P10253 1/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
S1PR2 O95136 1/20 0.40
S1PR4 O95977 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7221454 0.83 MEN1 (0.55) ALDH1A1MAPTKDM4EGAACYP2D6
SCHEMBL13965835 0.79 ALDH1A1 (0.46) ALDH1A1LMNAMAPTMAPK1KDM4E
SCHEMBL3741348 0.76 ALDH1A1 (0.50) ALDH1A1LMNAMAPTMAPK1KDM4E
SCHEMBL29444840 0.75 MEN1 (0.56) ALDH1A1KDM4EGLASLC2A4GAA
Hydrochloric Acid SCHEMBL5395461 0.74 ALDH1A1 (0.49) ALDH1A1LMNAKDM4EGLASLC2A4
SCHEMBL19841127 0.74 ALDH1A1 (0.40) ALDH1A1LMNAMAPTMAPK1KDM4E
SCHEMBL3266830 0.73 HRH4 (0.58) ALDH1A1LMNAMAPTKDM4EGLA
SCHEMBL6831037 0.72 ALDH1A1 (0.54) ALDH1A1KDM4EGLASLC2A4CYP3A4
SCHEMBL8510037 0.72 CYP3A4 (0.52) ALDH1A1LMNAMAPTMAPK1GAA
SCHEMBL211808 0.72 GAA (0.49) ALDH1A1LMNAMAPTMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100167069-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF CORPORATION (US) 2010-07-01 US disclosed