Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25641311 | 0.80 | ALOX5AP (0.35) | ALOX5AP | |
| SCHEMBL12972057 | 0.79 | ALOX5AP (0.34) | ALOX5AP | |
| SCHEMBL3294812 | 0.78 | GRIN2D (0.34) | — | |
| SCHEMBL14931210 | 0.77 | ALOX5AP (0.31) | ALOX5AP | |
| SCHEMBL32688892 | 0.76 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL32689235 | 0.76 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL4387181 | 0.75 | ALOX5AP (0.30) | ALOX5AP | |
| SCHEMBL152170 | 0.73 | ALOX5AP (0.37) | ALOX5APHSD11B1 | |
| SCHEMBL32688545 | 0.72 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL10305805 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047581-A1 | HEXAHYDROBENZOPYRAZOLE DERIVATIVE AND PREPARATION THEREFOF | 四川海思科制药有限公司 | 2021-03-18 | — | — | WO | disclosed |
| US-10875996-B2 | Methacrylic copolymer and molded article | KURARAY CO., LTD. (JP) | 2020-12-29 | — | — | US | disclosed |
| US-10875996-B2 | Methacrylic copolymer and molded article | KURARAY CO., LTD. (JP) | 2020-12-29 | — | — | US | disclosed |
| US-20200317902-A1 | METHACRYLIC COPOLYMER AND MOLDED ARTICLE | KURARAY CO., LTD. (JP) | 2020-10-08 | — | — | US | disclosed |
| US-20200317902-A1 | METHACRYLIC COPOLYMER AND MOLDED ARTICLE | KURARAY CO., LTD. (JP) | 2020-10-08 | — | — | US | disclosed |
| EP-3564275-A1 | METHACRYLIC COPOLYMER AND MOLDED ARTICLE | Kuraray Co., Ltd. (JP) | 2019-11-06 | — | — | EP | disclosed |
| EP-2451812-B1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-9682979-B2 | Substituted pyrazolo [1,5-A] pyrimidine compounds as TRK kinase inhibitors | ARRAY BIOPHARMA, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20170114069-A1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS | ARRAY BIOPHARMA, INC. | 2017-04-27 | — | — | US | disclosed |
| US-20150031667-A1 | Substituted Pyrazolo [1,5-A] Pyrimidine Compounds as TRK Kinase Inhibitors | ARRAY BIOPHARMA, INC. | 2015-01-29 | — | — | US | disclosed |
| EP-2105794-A1 | Novel photoacid generator, resist composition, and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2009-09-30 | — | — | EP | disclosed |
| EP-2103592-A2 | Hydroxyl-containing monomer, polymer, resist composition, and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |
| EP-2101217-A1 | Sulfonium salt-containing polymer, resist compositon, and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-2100887-A1 | Lactone-containing compound, polymer, resist composition, and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-2033966-A2 | Movel photoacid generators, resist compositons, and patterning processes | Shin-Etsu Chemical Co., Ltd. (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-20080008962-A1 | Polymerizable ester compounds, polymers, resist compositions and patterning process | SHIN-ETSU CHEMICAL CO., LTD. | 2008-01-10 | — | — | US | disclosed |
| US-20080008962-A1 | Polymerizable ester compounds, polymers, resist compositions and patterning process | SHIN-ETSU CHEMICAL CO., LTD. | 2008-01-10 | — | — | US | disclosed |
| US-20080008962-A1 | Polymerizable ester compounds, polymers, resist compositions and patterning process | SHIN-ETSU CHEMICAL CO., LTD. | 2008-01-10 | — | — | US | disclosed |
| US-7214828-B2 | Durable coating compositions containing novel aspartic amine compounds | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| JP-2001310910-A | 2-(METH)ACRYLOYLOXYMETHYL-2-METHYLBICYCLO[2.2.1]HEPTANE, METHOD OF MANUFACTURE, METHOD OF PURIFICATION OF RAW MATERIAL ALCOHOL, METHOD OF MANUFACTURE RAW MATERIAL ALDEHYDE AND (CO)POLYMER OF THE SAME | MITSUBISHI RAYON CO LTD | 2001-11-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114069-A1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS | TXK, FRK, LTK | ALOX5AP 3729/4885BCHE 3900/4885ACHE 1548/4885 |
| US-20150031667-A1 | Substituted Pyrazolo [1,5-A] Pyrimidine Compounds as TRK Kinase Inhibitors | TXK, FRK, LTK | ALOX5AP 3729/4885BCHE 3900/4885ACHE 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.