SCHEMBL3687946

SCHEMBL3687946

CNC(=O)C(=NOC)c1ccccc1COc1ccc(C=C(Br)Br)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.51
MRGPRX4 Q96LA9 5/20 0.43
RAB9A P51151 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
NPC1 O15118 3/20 0.41
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.39
HTT P42858 1/20 0.39
S1PR4 O95977 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
S1PR1 P21453 1/20 0.39
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GPR35 Q9HC97 1/20 0.39
NFKB1 P19838 2/20 0.38
NFKB2 Q00653 2/20 0.38
RELA Q04206 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3687943 1.00 HIF1A (0.51) HIF1AMRGPRX4RAB9ASMN1; SMN2NPC1
SCHEMBL3687099 0.92 HIF1A (0.52) HIF1AMRGPRX4RAB9ASMN1; SMN2NPC1
SCHEMBL3687101 0.92 HIF1A (0.52) HIF1AMRGPRX4RAB9ASMN1; SMN2NPC1
SCHEMBL3692884 0.91 HIF1A (0.62) HIF1AMRGPRX4RAB9ASMN1; SMN2NPC1
SCHEMBL3683433 0.90 HIF1A (0.64) HIF1ARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL3683435 0.90 HIF1A (0.64) HIF1ARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL3688032 0.90 HIF1A (0.52) HIF1ARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL3688027 0.90 HIF1A (0.52) HIF1ARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL3687974 0.90 HIF1A (0.52) HIF1AMRGPRX4RAB9ASMN1; SMN2NPC1
SCHEMBL3687980 0.90 HIF1A (0.52) HIF1AMRGPRX4RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
CN-101888993-B Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORP 2013-08-21 CN claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP claimed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
CN-101888993-B Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORP 2013-08-21 CN disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP disclosed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885MRGPRX4 1060/4885RAB9A 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.