SCHEMBL3688032

SCHEMBL3688032

CNC(=O)C(=NOC)c1ccccc1COc1ccc(C=C(Br)Br)cc1Br

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.52
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
TLR9 Q9NR96 1/20 0.40
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.37
ESRRA P11474 1/20 0.36
FOLH1 Q04609 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3688027 1.00 HIF1A (0.52) HIF1AKDM4EHPGDTLR9RAB9A
SCHEMBL3697793 0.92 HIF1A (0.51) HIF1AKDM4EHPGDTLR9RAB9A
SCHEMBL3697791 0.92 HIF1A (0.51) HIF1AKDM4EHPGDTLR9RAB9A
SCHEMBL3687980 0.91 HIF1A (0.52) HIF1ARAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL3687974 0.91 HIF1A (0.52) HIF1ARAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL3683435 0.91 HIF1A (0.64) HIF1AHPGDRAB9ASMN1; SMN2NPC1
SCHEMBL3683433 0.91 HIF1A (0.64) HIF1AHPGDRAB9ASMN1; SMN2NPC1
SCHEMBL3686962 0.90 HIF1A (0.63) HIF1AKDM4EHPGDTLR9RAB9A
SCHEMBL3687946 0.90 HIF1A (0.51) HIF1AHPGDRAB9ASMN1; SMN2NPC1
SCHEMBL3687943 0.90 HIF1A (0.51) HIF1AHPGDRAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP claimed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885KDM4E 143/4885HPGD 4555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.