Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 4/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PFKFB4 | Q16877 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684890 | 0.99 | MEN1 (0.43) | MEN1KMT2ANPSR1L3MBTL1CMA1 | |
| SCHEMBL3684064 | 0.84 | NPSR1 (0.44) | MEN1KMT2ANPSR1L3MBTL1CMA1 | |
| SCHEMBL3687954 | 0.83 | NPSR1 (0.40) | MEN1KMT2ANPSR1L3MBTL1CMA1 | |
| SCHEMBL787942 | 0.79 | CMA1 (0.51) | NPSR1L3MBTL1CMA1PFKFB3PFKFB4 | |
| SCHEMBL13508383 | 0.76 | CA1 (0.44) | NPSR1L3MBTL1CMA1PFKFB3LMNA | |
| SCHEMBL2226181 | 0.76 | NPSR1 (0.60) | NPSR1L3MBTL1CMA1PFKFB3PFKFB4 | |
| SCHEMBL3946161 | 0.76 | PFKFB3 (0.53) | NPSR1L3MBTL1CMA1PFKFB3PFKFB4 | |
| Hydrochloric Acid SCHEMBL6712744 | 0.75 | NPSR1 (0.59) | NPSR1L3MBTL1CMA1PFKFB3PFKFB4 | |
| SCHEMBL787895 | 0.74 | PFKFB3 (0.57) | NPSR1L3MBTL1CMA1PFKFB3PFKFB4 | |
| SCHEMBL2895391 | 0.74 | GPR35 (0.54) | MEN1KMT2ANPSR1KIF11DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | ELI LILLY AND COMPANY (US) | 2006-09-28 | — | — | US | disclosed |
| EP-1597248-A2 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004073606-A2 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | PPARD, PPARA, PPARG | MEN1 4858/4885KMT2A 2003/4885NPSR1 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.