SCHEMBL3688339

SCHEMBL3688339

O=[N+]([O-])C1OCC(Br)CO1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28808309 0.71
SCHEMBL2895095 0.69
SCHEMBL877528 0.65 ALDH1A1 (0.32) ALDH1A1
SCHEMBL10501292 0.64
SCHEMBL28060726 0.62 ALDH1A1 (0.30) ALDH1A1
SCHEMBL7252280 0.62 ALDH1A1 (0.30) ALDH1A1
SCHEMBL3287236 0.56
SCHEMBL887970 0.51 MEN1 (0.75) ALDH1A1
SCHEMBL8577936 0.51
SCHEMBL28392434 0.50 MEN1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659340-B1 Preservation of column materials in aqueous solutions ROCHE DIAGNOSTICS GMBH (DE) 2000-07-05 EP claimed
EP-0659340-A1 Preservation of column materials in aqueous solutions Roche Diagnostics GmbH (DE) 1995-06-28 EP claimed
EP-0490567-A1 The use of halogen-containing organic stabilizers for 3-isothiazolones ROHM AND HAAS COMPANY (US) 1992-06-17 EP claimed
US-4927946-A Process for the preparation of 5-bromo-5-nitro-1,3-dioxane HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-05-22 US claimed
WO-2024123828-A1 NOOTKATONE FOR THE TREATMENT OF DIABETIC DERMOPATHY OR DIABETIC PERIPHERAL NEUROPATHY ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2024123826-A1 NOOTKATONE FOR IMPROVING THE APPEARANCE OF SKIN ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2024123825-A1 NOOTKATONE FOR THE TREATMENT OF PSORIASIS OR ATOPIC DERMATITIS ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2024123824-A1 NOOTKATONE FOR THE TREATMENT OF PRURITUS ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2024123830-A1 NOOTKATONE FOR THE TREATMENT OF GUT OR ABDOMINAL PAIN ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
US-11833115-B2 Mineral based compositions and use thereof ANJON BIOLOGICS, INC. (US) 2023-12-05 US disclosed
EP-4277617-A1 COMPOSITIONS FOR SKINCARE AND USE THEREOF Anjon Biologics Inc. (US) 2023-11-22 EP disclosed
US-20230000736-A1 COMPOSITIONS FOR SKINCARE AND USE THEREOF ANJON BIOLOGICS, INC. (US) 2023-01-05 US disclosed
EP-1267697-B1 MOIST WIPES (II) COGNIS IP MAN GMBH (DE) 2008-08-13 EP disclosed
US-20080112909-A1 COMPOSITIONS FOR PROVIDING COLOR TO ANIMATE OBJECTS AND RELATED METHODS PPG INDUSTRIES OHIO, INC. (US) 2008-05-15 US disclosed
US-7297678-B2 Use of repeat sequence protein polymers in personal care compositions GENENCOR INTERNATIONAL, INC. (US) 2007-11-20 US disclosed
US-20060243323-A1 Emulsions for lignocellulosic products, methods of their manufacture, improved lignocellulosic products and methods for their manufacuture ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT (CA) 2006-11-02 US disclosed
US-20040180027-A1 Use of repeat sequence protein polymers in personal care compositions DANISCO US INC. 2004-09-16 US disclosed
WO-1999015512-A1 ISOTHIAZOLONE PREPARATION AND PROCESS FOR PRODUCING THE SAME CHEMICREA INC. (JP) 1999-04-01 WO disclosed
US-5142058-A For metal working fluids and latex paints ROHM AND HAAS COMPANY (US) 1992-08-25 US disclosed
EP-0490567-A1 The use of halogen-containing organic stabilizers for 3-isothiazolones ROHM AND HAAS COMPANY (US) 1992-06-17 EP disclosed