Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069372 | 0.93 | MMP13 (0.80) | MMP13SLC22A8 | |
| SCHEMBL8068217 | 0.91 | MMP13 (0.80) | MMP13SLC22A8 | |
| SCHEMBL8068220 | 0.91 | MMP13 (0.80) | MMP13SLC22A8 | |
| SCHEMBL8065056 | 0.89 | MMP13 (0.80) | MMP13SLC22A8 | |
| SCHEMBL8068187 | 0.88 | MMP13 (0.88) | MMP13SLC22A8 | |
| SCHEMBL8065163 | 0.88 | MMP13 (0.88) | MMP13SLC22A8 | |
| SCHEMBL3805121 | 0.88 | MMP13 (1.00) | MMP13SLC22A8 | |
| SCHEMBL3805117 | 0.88 | MMP13 (1.00) | MMP13SLC22A8 | |
| SCHEMBL8066652 | 0.88 | MMP13 (0.84) | MMP13SLC22A8 | |
| SCHEMBL8066857 | 0.88 | MMP13 (0.86) | MMP13SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101815710-A | Pyrimidine and pyridine derivatives, their pharmaceutical use and compositions | PFIZER | 2010-08-25 | — | — | CN | disclosed |
| EP-2185537-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | Pfizer Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |