Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CPS1 | P31327 | 4/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280887 | 0.91 | LMNA (0.48) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL3694917 | 0.91 | LMNA (0.48) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL3696107 | 0.91 | ITGAL (0.48) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL3688915 | 0.91 | ITGAL (0.48) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL3685103 | 0.90 | ABCB1 (0.45) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL3685105 | 0.90 | ABCB1 (0.45) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL3693494 | 0.88 | LMNA (0.45) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL4879941 | 0.88 | LMNA (0.46) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL4879944 | 0.88 | LMNA (0.46) | MEN1LMNAKMT2AHPGDGAA | |
| SCHEMBL3687219 | 0.88 | MEN1 (0.44) | MEN1LMNAKMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | claimed |
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |