Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.48 |
| ▸ | FNTB | P49356 | 15/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054557 | 0.85 | FNTA (0.49) | FNTAFNTBMEN1KMT2A | |
| SCHEMBL3683099 | 0.82 | FNTA (0.51) | FNTAFNTBMEN1KMT2A | |
| SCHEMBL3501175 | 0.81 | FNTA (0.50) | FNTAFNTBMEN1KMT2A | |
| SCHEMBL5823936 | 0.81 | FNTA (0.63) | FNTAFNTB | |
| SCHEMBL3501377 | 0.80 | FNTA (0.57) | FNTAFNTBMEN1KMT2AALDH1A1 | |
| SCHEMBL3502917 | 0.80 | FNTA (0.55) | FNTAFNTBMEN1KMT2AALDH1A1 | |
| SCHEMBL3499785 | 0.80 | FNTA (0.55) | FNTAFNTBMEN1KMT2AALDH1A1 | |
| SCHEMBL2364392 | 0.80 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL3502196 | 0.80 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL3499709 | 0.79 | FNTA (0.54) | FNTAFNTBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057028-A9 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-09-02 | — | — | WO | disclosed |