Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.63 |
| ▸ | FNTB | P49356 | 14/20 | 0.63 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499535 | 0.92 | FNTA (0.75) | FNTAFNTBACKR3 | |
| SCHEMBL3501149 | 0.90 | FNTA (0.75) | FNTAFNTBACKR3 | |
| SCHEMBL3502196 | 0.90 | FNTA (0.60) | FNTAFNTBACKR3 | |
| SCHEMBL3502422 | 0.88 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL3502908 | 0.88 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL6312671 | 0.87 | FNTA (0.49) | FNTAFNTBACKR3 | |
| SCHEMBL3501593 | 0.87 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL3499170 | 0.86 | FNTA (0.61) | FNTAFNTBACKR3 | |
| SCHEMBL3500599 | 0.86 | FNTA (0.62) | FNTAFNTB | |
| SCHEMBL3501412 | 0.85 | FNTA (0.74) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005089515-A9 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | BRIGHAM & WOMENS HOSPITAL (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2005089515-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2005-09-29 | — | — | WO | disclosed |