SCHEMBL3689065

SCHEMBL3689065

C#Cc1cccc2cc3c([Si](C)(C)C)c4cc5ccccc5cc4c([Si](C)(C)C)c3cc12

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HSD17B10 Q99714 2/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
NQO1 P15559 1/20 0.31
CYP1B1 Q16678 2/20 0.31
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
CYP1A1 P04798 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3465692 0.85 NQO1 (0.33) ELANEALDH1A1HPGDNQO1KDM4E
SCHEMBL2541430 0.84
SCHEMBL648767 0.84
SCHEMBL30918302 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP1A2HPGDNQO1
SCHEMBL937286 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP1A2HPGDNQO1
SCHEMBL28776208 0.81 ALDH1A1 (0.45) ALDH1A1HSD17B10CYP1A2HPGDNQO1
SCHEMBL5478906 0.81 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP1A2HPGDNQO1
SCHEMBL11126907 0.81 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP1A2HPGDNQO1
SCHEMBL5438141 0.80 CYP1B1 (0.41) ALDH1A1HSD17B10CYP1A2HPGDCYP1B1
SCHEMBL6033716 0.80 ALDH1A1 (0.43) ALDH1A1HSD17B10CYP1A2HPGDNQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687830-B1 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS MERCK PATENT GMBH (DE) 2010-07-28 EP disclosed
EP-1808866-A1 Organic semiconducting layer formulations comprising polyacenes and organic binder polymers Merck Patent GmbH (DE) 2007-07-18 EP disclosed
EP-1783781-A2 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS Merck Patent GmbH (DE) 2007-05-09 EP disclosed