SCHEMBL3689459

SCHEMBL3689459

C=CCOC(=O)c1ccc(C)c(C)c1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.53
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 3/20 0.47
TSHR P16473 3/20 0.47
MAPT P10636 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 3/20 0.40
LMNA P02545 2/20 0.40
GAA P10253 2/20 0.40
MAPK1 P28482 1/20 0.40
HPGD P15428 2/20 0.39
TP53 P04637 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 1/20 0.37
SNCA P37840 1/20 0.37
ALOX12 P18054 1/20 0.36
RHOA P61586 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5772028 0.83 TSHR (0.52) ALDH1A1HSD17B10TSHRMAPTMEN1
SCHEMBL27438623 0.82 CYP3A4 (0.61) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL429498 0.81 CYP3A4 (0.50) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL9717642 0.79 CYP3A4 (0.69) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL429496 0.77 CYP3A4 (0.56) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL9422015 0.77 CYP3A4 (0.67) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL28431291 0.77 CYP3A4 (0.67) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL302697 0.77 TSHR (0.55) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL3969049 0.76 CA12 (0.42) ALDH1A1HSD17B10TSHRMAPTMEN1
SCHEMBL11800019 0.76 CYP3A4 (0.65) CYP3A4ALDH1A1HSD17B10TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
US-7803298-B2 Molding material, molded part, and method for manufacturing them SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2010-09-28 US disclosed
US-20090085260-A1 BIODEGRADABLE MATERIAL AND PROCESS FOR PRODUCING THE SAME JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2009-04-02 US disclosed
US-20090030160-A1 Polylactic Acid Complex and Production Method Thereof SUMITOMO ELECTRIC FINE POLYMER INC. (JP) 2009-01-29 US disclosed
US-20080213209-A1 Process for Producing Cross-Linked Material of Polylactic Acid and Cross-Linked Material of Polylactic Acid SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2008-09-04 US disclosed
US-20080036119-A1 Molding material, molded part, and method for manufacturing them SUMITOMO ELECTRIC FINE POLYMER, INC. 2008-02-14 US disclosed
US-20060160984-A1 Biodegradable material and process for producing the same JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2006-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085260-A1 BIODEGRADABLE MATERIAL AND PROCESS FOR PRODUCING THE SAME TST, PCMT1, XRCC6 CYP3A4 1680/4885ALDH1A1 1504/4885HSD17B10 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.