SCHEMBL3689704

SCHEMBL3689704

Cc1cc(=O)oc2cc(N([Si](C)(C)C)[Si](C)(C)C)ccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.66
HSD17B10 Q99714 7/20 0.66
IGLV6-57 P01721 6/20 0.66
HPGD P15428 6/20 0.66
GLA P06280 5/20 0.66
CASP1 P29466 3/20 0.66
CASP7 P55210 3/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
CYP3A4 P08684 2/20 0.66
MAPK1 P28482 1/20 0.66
ATM Q13315 1/20 0.66
HIF1A Q16665 1/20 0.66
KDM4E B2RXH2 9/20 0.57
GAA P10253 5/20 0.57
CA9 Q16790 5/20 0.57
CA12 O43570 4/20 0.57
CA1 P00915 3/20 0.57
LMNA P02545 2/20 0.57
AKR1B1 P15121 2/20 0.57
MCL1 Q07820 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401382 0.83 IGLV6-57 (0.72) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL67970 0.83 IGLV6-57 (0.72) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL10337820 0.82 ALDH1A1 (0.68) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL67108 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL13788746 0.79 ALDH1A1 (0.68) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL24590362 0.79 IGLV6-57 (0.70) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL29362472 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL384286 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL3834472 0.78 IGLV6-57 (0.67) ALDH1A1HSD17B10IGLV6-57HPGDGLA
SCHEMBL22416802 0.78 IGLV6-57 (1.00) ALDH1A1HSD17B10IGLV6-57HPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231720-B1 FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING BRIDGESTONE CORP (JP) 2013-08-14 EP disclosed
US-8236892-B2 Functionalized polymer and methods for making and using BRIDGESTONE CORPORATION (JP) 2012-08-07 US disclosed
US-20100311899-A1 FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING BRIDGESTONE CORPORATION (JP) 2010-12-09 US disclosed