Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213208 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL10262394 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL6748385 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL5448 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL1660832 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL24214 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL15665811 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL1356717 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL3834 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE | |
| SCHEMBL15952 | 1.00 | PRKCA (0.52) | PRKCAMAPTMAPK1LMNAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166837-A1 | DRUG COMBINATION FOR THE TREATMENT OF SKIN DISORDERS | Prugen, Inc. (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008156798-A1 | DRUG COMBINATION FOR THE TREATMENT OF SKIN DISORDERS | PRUGEN, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-1061896-A1 | COSMETIC METHOD OF TREATING SKIN | UNILEVER PLC (GB) | 2000-12-27 | — | — | EP | disclosed |
| US-6042841-A | Cosmetic method of treating skin | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) | 2000-03-28 | — | — | US | disclosed |
| US-6036963-A | COSMETICS FOR SKIN WITH RETINOL, RETINOIC ACID, RETINAL, RETINYL ESTER AND MIXTURES WITH LACTONES AND VEHICLES | CHESEBROUGH-PONDS'S USA CO., DIVISION OF CONOPCO, INC. (US) | 2000-03-14 | — | — | US | disclosed |
| WO-1999055300-A1 | SKIN CARE COSMETIC COMPOSITIONS | UNILEVER PLC (GB) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999047110-A1 | COSMETIC METHOD OF TREATING SKIN | UNILEVER PLC (GB) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999037281-A1 | SKIN CARE COSMETIC METHOD AND SYSTEM | UNILEVER PLC (GB) | 1999-07-29 | — | — | WO | disclosed |
| US-5744148-A | CONTAINING A HYDROXY ACID | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1998-04-28 | — | — | US | disclosed |