Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | MAX | P61244 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15061627 | 0.73 | — | — | |
| SCHEMBL17077371 | 0.69 | EGFR (0.42) | ALDH1A1MAPTKMT2AEGFRMYC | |
| SCHEMBL813750 | 0.69 | EGFR (0.45) | ALDH1A1MAPTEGFRMYCMAX | |
| SCHEMBL17077372 | 0.69 | EGFR (0.42) | ALDH1A1MAPTKMT2AEGFRMYC | |
| SCHEMBL809489 | 0.69 | EGFR (0.45) | ALDH1A1MAPTEGFRMYCMAX | |
| SCHEMBL9045857 | 0.69 | MYC (0.34) | EGFRMYCMAX | |
| SCHEMBL9045867 | 0.69 | MYC (0.34) | EGFRMYCMAX | |
| SCHEMBL812891 | 0.67 | EGFR (0.43) | ALDH1A1MAPTEGFRMYCMAX | |
| SCHEMBL809563 | 0.67 | EGFR (0.43) | ALDH1A1MAPTEGFRMYCMAX | |
| SCHEMBL9287750 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674741-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-03-09 | — | — | US | disclosed |
| EP-1756172-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SRL (IT) | 2009-11-04 | — | — | EP | disclosed |
| US-20090118446-A1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2009-05-07 | — | — | US | disclosed |
| EP-1756172-A2 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005123784-A2 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-12-29 | — | — | WO | disclosed |