SCHEMBL9045867

SCHEMBL9045867

O=C1CC(=CC2CCCCC2)C(=O)O1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.34
MAX P61244 1/20 0.34
EGFR P00533 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9045857 1.00 MYC (0.34) MYCMAXEGFR
SCHEMBL6725425 0.78 MYC (0.37) MYCMAX
SCHEMBL3690294 0.69 ALDH1A1 (0.42) MYCMAXEGFR
SCHEMBL664703 0.67 DYRK1A (0.42) MYCMAXEGFR
SCHEMBL9256209 0.67 DYRK1A (0.42) MYCMAXEGFR
SCHEMBL9256212 0.67 DYRK1A (0.42) MYCMAXEGFR
SCHEMBL7771253 0.66
SCHEMBL775803 0.66
SCHEMBL38661147 0.66
SCHEMBL20122754 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0507534-B1 Succinic acid compounds KISSEI PHARMACEUTICAL (JP) 1996-02-28 EP disclosed
US-5202335-A Hypoglycemic, antidiabetic agents KISSEI PHARMACEUTICAL CO., LTD. (JP) 1993-04-13 US disclosed
EP-0507534-A1 Succinic acid compounds KISSEI PHARMACEUTICAL CO., LTD. (JP) 1992-10-07 EP disclosed