Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109156 | 0.95 | LMNA (0.32) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11637189 | 0.85 | LMNA (0.33) | LMNAKMT2ATSHRNPC1 | |
| SCHEMBL14796576 | 0.85 | GAA (0.45) | KMT2ATSHRALDH1A1 | |
| Acrylonitrile SCHEMBL28083337 | 0.85 | — | — | |
| SCHEMBL1068142 | 0.83 | BRD4 (0.33) | LMNACA12CA1CA2CA3 | |
| SCHEMBL1067025 | 0.83 | BRD4 (0.33) | LMNACA12CA1CA2CA3 | |
| SCHEMBL29127 | 0.83 | BRD4 (0.33) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11318608 | 0.83 | BRD4 (0.33) | LMNACA12CA1CA2CA3 | |
| SCHEMBL5068820 | 0.83 | BRD4 (0.33) | LMNACA12CA1CA2CA3 | |
| Propionic Acid SCHEMBL28130435 | 0.83 | LMNA (0.39) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812484-B1 | CORE-SHELL PARTICLES | MERCK PATENT GMBH (DE) | 2008-12-03 | — | — | EP | claimed |
| US-20100221525-A1 | NANOPARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-02 | — | — | US | disclosed |
| US-20100092761-A1 | NANOPARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2010-04-15 | — | — | US | disclosed |
| EP-2152800-A1 | CORE-SHELL PARTICLES WITH ENCAPSULATED BROAD SPECTRUM ABSORBER CONTRAST AGENT | Unilever PLC (GB) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008141972-A1 | CORE-SHELL PARTICLES WITH ENCAPSULATED BROAD SPECTRUM ABSORBER CONTRAST AGENT | UNILEVER PLC (GB) | 2008-11-27 | — | — | WO | disclosed |
| US-20080248289-A1 | Zinc Oxide Nanoparticles | MERCK PATENT GESELLSCHAFT (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20080093586-A1 | Use Of Statistical Copolymers | KOCH MATTHIAS | 2008-04-24 | — | — | US | disclosed |
| US-20070282075-A1 | Use Of Statistical Copolymers | MERCK PATENT GMBH (DE) | 2007-12-06 | — | — | US | disclosed |
| US-7291394-B2 | Composite material containing a core-covering particle | MERCK PATENT GMBH (DE) | 2007-11-06 | — | — | US | disclosed |
| US-20070178307-A1 | Use of core-shell particles | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20050228072-A1 | Composite material containing a core-covering particle | MERCK PATENT GMBH (DE) | 2005-10-13 | — | — | US | disclosed |
| US-20050145037-A1 | Extension and upsetting sensor | MERCK PATENT GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| US-20050142343-A1 | Moulded bodies consisting of core-shell particles | MERCK PATENT GMBH (DE) | 2005-06-30 | — | — | US | disclosed |
| US-20040253443-A1 | Moulded bodies consisting of core-shell particles | MERCK PATENT GMBH (DE) | 2004-12-16 | — | — | US | disclosed |
| US-6337131-B1 | Core-shell particles and preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-0807268-B1 | CROSSLINKED TINTED POLYMERS | NOVARTIS AG (CH) | 1999-06-30 | — | — | EP | disclosed |
| US-5871675-A | POLYVINYL ALCOHOL DERIVATIVES, CONTACT LENSES | NOVARTIS AG. (CH) | 1999-02-16 | — | — | US | disclosed |
| EP-0807268-A1 | CROSSLINKED TINTED POLYMERS | Novartis AG (CH) | 1997-11-19 | — | — | EP | disclosed |
| US-5665840-A | CONTACT LENSES, CROSSLINKED, HYDROLYSED VINYL ACETATE-VINYLPYRROLIDONE COPOLYMER | NOVARTIS CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| WO-1996024076-A1 | CROSSLINKED TINTED POLYMERS | NOVARTIS AG (CH) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080093586-A1 | Use Of Statistical Copolymers | PDS5A, PDS5B, CD44 | LMNA 3130/4885CA12 2363/4885CA1 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.