Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693904 | 0.96 | CYP1A2 (0.49) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL3685490 | 0.95 | ELANE (0.50) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL2853191 | 0.89 | ELANE (0.41) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL3688130 | 0.89 | CYP1A2 (0.40) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL5528867 | 0.79 | ALDH1A1 (0.59) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL4129142 | 0.76 | ALDH1A1 (0.59) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL21922648 | 0.74 | NPC1 (0.48) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL3091326 | 0.73 | ALDH1A1 (0.61) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL18984663 | 0.73 | ELANE (0.55) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 | |
| SCHEMBL13936313 | 0.73 | PTPRC (0.53) | CYP1A2CYP3A4TSHRCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231720-B1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORP (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-8236892-B2 | Functionalized polymer and methods for making and using | BRIDGESTONE CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100311899-A1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |