Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408109 | 0.80 | FFAR1 (0.39) | HSD17B10ALDH1A1KDM4E | |
| SCHEMBL9408115 | 0.80 | FFAR1 (0.39) | HSD17B10ALDH1A1KDM4E | |
| SCHEMBL8384841 | 0.80 | CYP2A6 (0.50) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL30635304 | 0.80 | CYP2A6 (0.50) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL30635286 | 0.80 | CYP2A6 (0.50) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL104811 | 0.78 | APP (0.32) | — | |
| SCHEMBL4956384 | 0.78 | CYP2A6 (0.69) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL31171 | 0.78 | CYP2A6 (0.69) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL25245965 | 0.76 | CYP2A6 (0.46) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL14662561 | 0.76 | CYP2A6 (0.46) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9327269-B2 | Stationary phase | DAICEL CORPORATION (JP) | 2016-05-03 | — | — | US | claimed |
| US-20150182943-A1 | STATIONARY PHASE | DAICEL CORPORATION (JP) | 2015-07-02 | — | — | US | claimed |
| EP-2876439-A1 | STATIONARY PHASE | Daicel Corporation (JP) | 2015-05-27 | — | — | EP | claimed |
| US-20090300800-A1 | D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation | BASF PLANT SCIENCE GMBH (DE) | 2009-12-03 | — | — | US | claimed |
| US-20070248996-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | PARAECIS PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | US | claimed |
| US-20060014696-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | PRAECIS PHARMACEUTICALS, INC. (US) | 2006-01-19 | — | — | US | claimed |
| EP-0929574-B1 | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2005-06-29 | — | — | EP | claimed |
| US-20020103134-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | PRAECIS PHARMACEUTICALS INC. | 2002-08-01 | — | — | US | claimed |
| US-5985242-A | PEPTIDE OF 3 TO 5 D-AMINO ACIDS; MAY BE MODIFIED AT AMINO-AND/OR CARBOXY TERMINUS; FOR TREATMENT OF AMYLOIDOSIS, ALZHEIMER'S DISEASE | PRAECIS PHARMACEUTICALS, INC. (US) | 1999-11-16 | — | — | US | claimed |
| EP-0929574-A1 | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998008868-A9 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | — | 1998-05-28 | — | — | WO | claimed |
| WO-1998008868-A1 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 1998-03-05 | — | — | WO | claimed |
| EP-0006123-B1 | A PTERIDINE DERIVATIVE AND A PROCESS FOR THE PREPARATION OF 10-DEAZAAMINOPTERIN AND ITS DERIVATIVES FROM THE PTERIDINE DERIVATIVE | Southern Research Institute (US) | 1985-01-16 | — | — | EP | claimed |
| CN-117752790-A | In-situ injectable hydrogel anti-tumor drug delivery system based on novel photodynamic material, and preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| EP-4247805-A1 | COMPOUNDS AS PU. 1 INHIBITORS | S-Infinity Pharmceuticals (CN) | 2023-09-27 | — | — | EP | disclosed |
| CN-115044383-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element | JSR株式会社 | 2022-09-13 | — | — | CN | disclosed |
| WO-1998008868-A9 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | — | 1998-05-28 | — | — | WO | disclosed |
| EP-0842169-A1 | BENZOTHIOPHENE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1998008868-A1 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1997001549-A1 | BENZOTHIOPHENE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248996-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | APP, IAPP, BACE1 | CYP2A6 3217/4885HSD17B10 3094/4885ALDH5A1 4142/4885 |
| US-20020103134-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | IAPP, APP, VIP | CYP2A6 2880/4885HSD17B10 3036/4885ALDH5A1 3800/4885 |
| US-20060014696-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | APP, IAPP, BACE1 | CYP2A6 3217/4885HSD17B10 3094/4885ALDH5A1 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.