SCHEMBL8384841

SCHEMBL8384841

O=Cc1ccc(C#Cc2ccc(C=O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
ALDH1A1 P00352 5/20 0.48
EGFR P00533 1/20 0.44
TYR P14679 1/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP2A13 Q16696 1/20 0.44
FFAR1 O14842 2/20 0.43
APP P05067 1/20 0.41
ALDH1A3 P47895 2/20 0.41
ALDH3A1 P30838 1/20 0.41
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395469 0.92 ALDH5A1 (0.50) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL1816905 0.90 ALDH1A1 (0.59) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL25245965 0.89 CYP2A6 (0.46) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL3006203 0.88 EGFR (0.47) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL1814707 0.88 PTGS1 (0.44) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL29178204 0.88 CYP2A6 (0.41) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL4453443 0.88 CYP2A6 (0.73) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL1815162 0.88 HSD17B10 (0.73) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL28542466 0.88 ALDH5A1 (0.46) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL1221196 0.86 FFAR1 (0.44) CYP2A6HSD17B10ALDH5A1ABATALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066528-A1 Method for Synthesizing a Covalent Organic Framework Material YOCOF MAT SUZHOU CO LTD (CN) 2025-02-27 US claimed
CN-116178647-B Cobalt cyclopentadiene-based covalent organic framework material, preparation method and application thereof 中国石油大学(华东) 2025-02-14 CN claimed
CN-119039550-A Vinyl high-crystallinity covalent organic framework film, film sensor, preparation method and application thereof 南开大学 2024-11-29 CN claimed
CN-118852568-A Efficient, green and universal fusion synthesis method for covalent organic frameworks 浙江大学杭州国际科创中心 2024-10-29 CN claimed
CN-118526517-A Method for adsorbing enterogenic protein combined uremic toxin and precursor thereof 南开大学 2024-08-23 CN claimed
US-20240270883-A1 COVALENT ORGANIC FRAMEWORK AND CATALYST, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF ZHEJIANG UNIVERSITY (CN) 2024-08-15 US claimed
CN-114773556-B Green solid-phase synthesis method of covalent organic framework material 耀科新材料(苏州)有限公司 2024-06-04 CN claimed
CN-117624521-A Ionic covalent organic framework material, solid phase synthesis method and application thereof 耀科新材料(苏州)有限公司 2024-03-01 CN claimed
WO-2024037615-A1 IONIC COVALENT ORGANIC FRAMEWORK MATERIAL, SOLID-PHASE SYNTHESIS METHOD THEREOF, AND USE THEREOF 耀科新材料(天津)有限公司 2024-02-22 WO claimed
EP-4269471-A1 COVALENT ORGANIC FRAMEWORK AND CATALYST, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF Zhejiang University (CN) 2023-11-01 EP claimed
WO-2023124952-A1 GREEN SOLID-PHASE SYNTHESIS METHOD FOR COVALENT ORGANIC FRAMEWORK MATERIAL 张振杰 2023-07-06 WO claimed
CN-116178647-A Cobalt cyclopentadiene-based covalent organic framework material, preparation method and application thereof 中国石油大学(华东) 2023-05-30 CN claimed
CN-114773556-A Green solid-phase synthesis method of covalent organic framework material 南开大学 2022-07-22 CN claimed
WO-2022133843-A1 COVALENT ORGANIC FRAMEWORK AND CATALYST, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF 浙江大学 2022-06-30 WO claimed
CN-120136762-B Application of diamidino-containing compound and pharmaceutically-acceptable salt in antifungal 中国医学科学院医药生物技术研究所 2026-05-12 CN disclosed
CN-120192490-A Quinoline type covalent organic framework material, cyano-modified quinoline type covalent organic framework material, and preparation method and application thereof 广东工业大学 2025-06-24 CN disclosed
CN-120136762-A Application of diamidino-containing compound and pharmaceutically-acceptable salt in antifungal 中国医学科学院医药生物技术研究所 2025-06-13 CN disclosed
US-5681504-A LIQUID CRYSTAL DOPANTS ROLIC AG (CH) 1997-10-28 US disclosed
US-5498367-A LIQUID CRYSTALS, 2-(PHENYL ETHYNYLPHENYL)-1,3-DIOXOLANE-4,5-DICARBOXYLATES HOFFMANN-LA ROCHE INC. (US) 1996-03-12 US disclosed
EP-0675188-A1 Optically active tolane derivative F. Hoffmann-La Roche AG (CH) 1995-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240270883-A1 COVALENT ORGANIC FRAMEWORK AND CATALYST, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF CYP4F11, CYP4F12, CYP2F1 CYP2A6 432/4885HSD17B10 399/4885ALDH5A1 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.