Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695040 | 0.89 | PTPN1 (0.62) | PTPN1CA2CA1P2RX7MEN1 | |
| SCHEMBL3687863 | 0.84 | PTPN1 (0.57) | PTPN1CA2CA1MEN1KMT2A | |
| SCHEMBL6736251 | 0.82 | NPC1 (0.46) | PTPN1P2RX7MEN1KMT2APOLB | |
| SCHEMBL3690533 | 0.80 | PTPN1 (0.59) | PTPN1CA2CA1P2RX7MEN1 | |
| SCHEMBL3694407 | 0.80 | PTPN1 (0.59) | PTPN1CA2CA1MEN1KMT2A | |
| SCHEMBL3692501 | 0.79 | MAPT (0.59) | PTPN1CA2CA1MEN1KMT2A | |
| SCHEMBL3691442 | 0.79 | PTPN1 (0.51) | PTPN1CA2CA1MEN1KMT2A | |
| SCHEMBL6730112 | 0.78 | PTPN1 (0.57) | PTPN1CA2CA1MEN1KMT2A | |
| SCHEMBL31006760 | 0.77 | CA2 (0.67) | PTPN1CA2CA1MEN1KMT2A | |
| SCHEMBL3693721 | 0.76 | PTPN1 (0.79) | PTPN1CA2CA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241855-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2012-08-14 | — | — | US | claimed |
| EP-1325154-B1 | METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2007-08-01 | — | — | EP | claimed |
| US-7118868-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2006-10-10 | — | — | US | claimed |
| EP-1707642-A2 | Method for detecting cytosine methylations | Epigenomics AG (DE) | 2006-10-04 | — | — | EP | claimed |
| EP-1294945-B1 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2006-08-30 | — | — | EP | claimed |
| US-20040152080-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2004-08-05 | — | — | US | claimed |
| EP-1325154-A2 | METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS | Epigenomics AG (DE) | 2003-07-09 | — | — | EP | claimed |
| EP-1294945-A2 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | Epigenomics AG (DE) | 2003-03-26 | — | — | EP | claimed |
| WO-2002031186-A2 | METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2002-04-18 | — | — | WO | claimed |
| WO-2001098528-A2 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2001-12-27 | — | — | WO | claimed |
| US-8377638-B2 | Process for the detection of cytosine methylations | QIAGEN GMBH (DE) | 2013-02-19 | — | — | US | disclosed |
| US-8241855-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20100297614-A1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | QIAGEN GMBH (DE) | 2010-11-25 | — | — | US | disclosed |
| EP-1977011-B1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | QIAGEN GMBH (DE) | 2010-07-28 | — | — | EP | disclosed |
| EP-1977011-A1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | Qiagen GmbH (DE) | 2008-10-08 | — | — | EP | disclosed |
| EP-1707642-A2 | Method for detecting cytosine methylations | Epigenomics AG (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1294945-B1 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20040152080-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2004-08-05 | — | — | US | disclosed |
| EP-1294945-A2 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | Epigenomics AG (DE) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001098528-A2 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2001-12-27 | — | — | WO | disclosed |