Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.60 |
| ▸ | ACHE | P22303 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692089 | 1.00 | BCHE (0.60) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3695023 | 1.00 | BCHE (0.60) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3692497 | 0.90 | ALOX5 (0.54) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3692494 | 0.90 | FFAR1 (0.53) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3695611 | 0.90 | FFAR1 (0.53) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3682133 | 0.90 | BCHE (0.62) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3684640 | 0.90 | MAPT (0.59) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3682132 | 0.90 | MAPT (0.59) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL30383292 | 0.90 | BCHE (0.62) | BCHEACHESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3693312 | 0.87 | F3 (0.64) | BCHEACHENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | claimed |
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |