Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | UNG | P13051 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29661090 | 1.00 | CA12 (0.52) | CA12CA1CA2CA6CA9 | |
| SCHEMBL10933256 | 0.91 | ATM (0.46) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL1557619 | 0.84 | CA12 (0.68) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL20235879 | 0.84 | CA12 (0.68) | CA12CA1CA2CA6CA9 | |
| SCHEMBL24031434 | 0.82 | TTR (0.44) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL15573241 | 0.82 | CA12 (0.65) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL15571211 | 0.82 | CA12 (0.65) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL15571519 | 0.82 | CA12 (0.65) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL15572370 | 0.82 | CA12 (0.65) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL147366 | 0.82 | CA12 (0.71) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035761-A1 | High-throughput rna structure analysis | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2010-02-11 | — | — | US | claimed |
| WO-2007145940-A2 | HIGH-THROUGHPUT RNA STRUCTURE ANALYSIS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-12-21 | — | — | WO | claimed |
| US-20240254107-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2024-08-01 | — | — | US | disclosed |
| CN-118119608-A | RNA targeting ligands, compositions thereof, and methods of making and using the same | 北卡罗来纳查佩尔山大学 | 2024-05-31 | — | — | CN | disclosed |
| EP-4337653-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | The University of North Carolina at Chapel Hill (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022256382-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-12-08 | — | — | WO | disclosed |
| US-20220289688-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2022-09-15 | — | — | US | disclosed |
| CN-114901654-A | RNA-targeting ligands, compositions thereof, and methods of making and using the same | 北卡罗来纳查佩尔山大学 | 2022-08-12 | — | — | CN | disclosed |
| EP-4010332-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | The University of North Carolina at Chapel Hill (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021026245-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-02-11 | — | — | WO | disclosed |
| US-8318424-B2 | High-throughput RNA structure analysis | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-11-27 | — | — | US | disclosed |
| US-20100035761-A1 | High-throughput rna structure analysis | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2010-02-11 | — | — | US | disclosed |
| WO-2007145940-A2 | HIGH-THROUGHPUT RNA STRUCTURE ANALYSIS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145940-A2 | HIGH-THROUGHPUT RNA STRUCTURE ANALYSIS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289688-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | TARBP1, RNGTT, NSUN3 | CA12 4457/4885CA1 4798/4885CA2 4786/4885 |
| US-20100035761-A1 | High-throughput rna structure analysis | NSUN2, RNGTT, FBL | CA12 4123/4885CA1 4053/4885CA2 4655/4885 |
| US-20240254107-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | TARBP1, RNGTT, NSUN3 | CA12 4457/4885CA1 4798/4885CA2 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.