Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193761 | 0.92 | PPARG (0.38) | MAOBACKR3SLC16A3SLC16A1MCTS1 | |
| SCHEMBL13660625 | 0.90 | MAOB (0.36) | MAOBACKR3SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3693646 | 0.89 | MAOB (0.35) | MAOBACKR3SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3701718 | 0.88 | PTGES (0.40) | MAOBMAPTKMT2A | |
| SCHEMBL1193997 | 0.86 | MAOB (0.37) | MAOBACKR3ITGB3ITGA2BPARP1 | |
| SCHEMBL1177676 | 0.86 | MAOB (0.37) | MAOBACKR3ITGB3ITGA2BPARP1 | |
| SCHEMBL12871721 | 0.86 | MAOB (0.36) | MAOBACKR3ITGB3ITGA2BPARP1 | |
| SCHEMBL1178122 | 0.85 | ACKR3 (0.40) | MAOBACKR3SLC16A3SLC16A1MCTS1 | |
| SCHEMBL3690996 | 0.85 | ACKR3 (0.38) | MAOBACKR3SLC16A3SLC16A1MCTS1 | |
| SCHEMBL1193806 | 0.82 | PTGES (0.42) | MAOBACKR3ITGB3ITGA2BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |