Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698450 | 0.91 | BDKRB2 (0.35) | BDKRB2PTGESTP53CYP1A2CYP3A4 | |
| SCHEMBL1079989 | 0.89 | BDKRB2 (0.41) | BDKRB2TP53CYP1A2CYP3A4CYP2D6 | |
| Bicarbonate SCHEMBL1079990 | 0.88 | BDKRB2 (0.43) | BDKRB2TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1081746 | 0.86 | BDKRB2 (0.40) | BDKRB2CYP3A4 | |
| SCHEMBL1178266 | 0.86 | BDKRB2 (0.41) | BDKRB2PTGESTP53CYP1A2CYP3A4 | |
| SCHEMBL12872101 | 0.86 | BDKRB2 (0.41) | BDKRB2PTGESTP53CYP1A2CYP3A4 | |
| SCHEMBL12871694 | 0.85 | BDKRB2 (0.40) | BDKRB2PTGESTP53CYP1A2CYP3A4 | |
| SCHEMBL1178490 | 0.84 | BDKRB2 (0.36) | BDKRB2PTGESTP53CYP1A2CYP3A4 | |
| Bicarbonate SCHEMBL3704950 | 0.84 | C3AR1 (0.41) | BDKRB2PTGESTP53 | |
| SCHEMBL1178681 | 0.84 | MAOB (0.41) | BDKRB2PTGESMCHR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |