Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130605 | 0.93 | AAK1 (0.33) | AAK1HTR2ASLC6A4KCNH2MRGPRX4 | |
| SCHEMBL2131159 | 0.91 | AAK1 (0.35) | AAK1MRGPRX4 | |
| SCHEMBL2131156 | 0.91 | AAK1 (0.35) | AAK1MRGPRX4 | |
| SCHEMBL2130607 | 0.91 | MRGPRX4 (0.34) | AAK1MRGPRX4KDM4EHTTKMT2A | |
| SCHEMBL3704110 | 0.90 | PPARG (0.31) | HTR2ASLC6A4KCNH2MRGPRX4 | |
| SCHEMBL3704113 | 0.90 | PPARG (0.31) | HTR2ASLC6A4KCNH2MRGPRX4 | |
| SCHEMBL2128848 | 0.86 | MRGPRX4 (0.33) | AAK1MRGPRX4KDM4EHTTKMT2A | |
| SCHEMBL2128839 | 0.86 | MRGPRX4 (0.33) | AAK1MRGPRX4KDM4EHTTKMT2A | |
| SCHEMBL15354703 | 0.85 | MRGPRX4 (0.31) | MRGPRX4KDM4EHTTKMT2A | |
| SCHEMBL2129307 | 0.84 | MRGPRX4 (0.31) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452944-B1 | DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING THEM AS ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2014-09-10 | — | — | EP | disclosed |
| EP-2452944-A1 | DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2012-05-16 | — | — | EP | disclosed |