Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704110 | 1.00 | PPARG (0.31) | PPARGHTR2ASLC6A4KCNH2MRGPRX4 | |
| SCHEMBL2129305 | 0.94 | PPARG (0.31) | PPARGHTR2ASLC6A4KCNH2 | |
| SCHEMBL2129307 | 0.91 | MRGPRX4 (0.31) | PPARGMRGPRX4 | |
| SCHEMBL2131502 | 0.91 | PTGDR2 (0.33) | PPARGMRGPRX4 | |
| SCHEMBL2131508 | 0.91 | PTGDR2 (0.33) | PPARGMRGPRX4 | |
| SCHEMBL3695441 | 0.90 | AAK1 (0.33) | HTR2ASLC6A4KCNH2MRGPRX4 | |
| SCHEMBL15284251 | 0.90 | S1PR1 (0.31) | — | |
| SCHEMBL15284247 | 0.90 | S1PR1 (0.31) | — | |
| SCHEMBL2130022 | 0.85 | PTGDR2 (0.33) | PPARGMRGPRX4 | |
| SCHEMBL2130031 | 0.85 | PTGDR2 (0.33) | PPARGMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452944-B1 | DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING THEM AS ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2014-09-10 | — | — | EP | disclosed |
| EP-2452944-A1 | DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2012-05-16 | — | — | EP | disclosed |