Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161618 | 0.84 | NPC1 (0.52) | KMT2ANPC1RAB9ATP53MEN1 | |
| SCHEMBL1743109 | 0.84 | MAP2K4 (0.41) | KMT2ANPC1RAB9AMAP2K4SCN9A | |
| SCHEMBL21223059 | 0.83 | MAP2K4 (0.47) | KMT2ANPC1RAB9AMAP2K4SCN9A | |
| SCHEMBL2478647 | 0.83 | MAP2K4 (0.45) | KMT2ANPC1RAB9AMAP2K4SCN9A | |
| SCHEMBL30376133 | 0.83 | NPC1 (0.46) | KMT2ANPC1RAB9AMAP2K4SCN9A | |
| SCHEMBL17632197 | 0.83 | NPC1 (0.46) | KMT2ANPC1RAB9AMAP2K4SCN9A | |
| SCHEMBL29510728 | 0.83 | MAP2K4 (0.45) | KMT2ANPC1RAB9AMAP2K4SCN9A | |
| SCHEMBL29248158 | 0.83 | MAP2K4 (0.39) | KMT2ANPC1RAB9AMAP2K4SCN9A | |
| SCHEMBL15122854 | 0.83 | FAAH (0.43) | KMT2ANPC1RAB9AMAP2K4SCN9A | |
| SCHEMBL30991736 | 0.83 | MAP2K4 (0.39) | KMT2ANPC1RAB9AMAP2K4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785651-B2 | Method for manufacturing a boronic acid ester compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20120123122-A1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | GENENTECH, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| CN-102361878-A | Process for preparing boronic acid ester compounds | SUMITOMO CHEMICAL CO | 2012-02-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123122-A1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | NISCH, BRSK1, BLK | KMT2A 1372/4885NPC1 759/4885RAB9A 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.