Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691580 | 1.00 | BCHE (0.56) | BCHEACHETLR9CRHBPCRHR2 | |
| SCHEMBL3687869 | 0.90 | BCHE (0.54) | BCHEACHETLR9KMT2ARAB9A | |
| SCHEMBL3688870 | 0.89 | MAOB (0.53) | TLR9KMT2ARELAMAPTPOLB | |
| SCHEMBL3692346 | 0.89 | BCHE (0.57) | BCHEP4HBABCG2CYP1B1 | |
| SCHEMBL3682839 | 0.89 | BCHE (0.57) | BCHEP4HBABCG2CYP1B1 | |
| SCHEMBL25184970 | 0.88 | BCHE (0.56) | BCHEACHETLR9CRHBPCRHR2 | |
| SCHEMBL30384875 | 0.88 | BCHE (0.56) | BCHEACHETLR9CRHBPCRHR2 | |
| SCHEMBL3691582 | 0.88 | BCHE (0.56) | BCHEACHETLR9CRHBPCRHR2 | |
| SCHEMBL3689248 | 0.87 | BCHE (0.60) | BCHEACHEKMT2ARAB9ACYP3A4 | |
| SCHEMBL3682843 | 0.87 | P4HB (0.57) | BCHEP4HBABCG2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |