Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693933 | 1.00 | BACE1 (0.34) | BACE1ACKR3HPGDTSHRALDH1A1 | |
| SCHEMBL1081296 | 0.92 | BACE1 (0.34) | BACE1ACKR3HPGDTSHRALDH1A1 | |
| SCHEMBL3697772 | 0.89 | C3AR1 (0.40) | ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL3695472 | 0.89 | C3AR1 (0.40) | ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL1193793 | 0.89 | LTA4H (0.35) | BACE1ACKR3HPGDTSHRALDH1A1 | |
| SCHEMBL3694157 | 0.89 | LTA4H (0.35) | BACE1ACKR3HPGDTSHRALDH1A1 | |
| SCHEMBL1193791 | 0.89 | LTA4H (0.35) | BACE1ACKR3HPGDTSHRALDH1A1 | |
| SCHEMBL1177679 | 0.87 | HPGD (0.35) | BACE1ACKR3HPGDTSHRALDH1A1 | |
| SCHEMBL1177677 | 0.87 | HPGD (0.35) | BACE1ACKR3HPGDTSHRALDH1A1 | |
| SCHEMBL1178010 | 0.87 | HPGD (0.35) | BACE1ACKR3HPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |