Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6123772 | 0.69 | HPGD (0.61) | HPGDALDH1A1SMN1; SMN2NOTUMADRA2A | |
| SCHEMBL18634020 | 0.68 | HPGD (0.50) | HPGDALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL7970165 | 0.67 | HPGD (0.57) | HPGDALDH1A1NOTUMKMT2AMEN1 | |
| SCHEMBL17951855 | 0.67 | HPGD (0.48) | HPGDNOTUMADRA2AADRA2BADRA2C | |
| SCHEMBL12190838 | 0.67 | HPGD (0.53) | HPGDALDH1A1SMN1; SMN2NOTUMADRA2A | |
| SCHEMBL496672 | 0.67 | HPGD (0.70) | HPGDALDH1A1NOTUMADRA2AADRA2B | |
| SCHEMBL30420919 | 0.67 | HPGD (0.70) | HPGDALDH1A1NOTUMADRA2AADRA2B | |
| SCHEMBL19350211 | 0.66 | HPGD (0.47) | HPGDALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL28642675 | 0.66 | HPGD (0.42) | HPGDALDH1A1SMN1; SMN2NOTUMADRA2A | |
| SCHEMBL5231220 | 0.65 | HPGD (0.47) | HPGDALDH1A1NOTUMADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635640-B1 | NOVEL APPLICATIONS OF INDOLOINDOLE AND INDOLOQUINOLINE DYES | BIOSYNTH AG (CH) | 2019-07-10 | — | — | EP | disclosed |
| US-9157917-B2 | Applications of Indoloindole and Indoloquinoline dyes | BIOSYNTH AG (CH) | 2015-10-13 | — | — | US | disclosed |
| US-9157917-B2 | Applications of Indoloindole and Indoloquinoline dyes | BIOSYNTH AG (CH) | 2015-10-13 | — | — | US | disclosed |
| US-20140377783-A1 | NOVEL APPLICATIONS OF INDOLOINDOLE AND INDOLOQUINOLINE DYES | BIOSYNTH AG (CH) | 2014-12-25 | — | — | US | disclosed |
| US-20140377783-A1 | NOVEL APPLICATIONS OF INDOLOINDOLE AND INDOLOQUINOLINE DYES | BIOSYNTH AG (CH) | 2014-12-25 | — | — | US | disclosed |
| EP-2635640-A1 | NOVEL APPLICATIONS OF INDOLOINDOLE AND INDOLOQUINOLINE DYES | Biosynth AG (CH) | 2013-09-11 | — | — | EP | disclosed |
| EP-2453021-A1 | Novel indicator compounds | Biosynth AG (CH) | 2012-05-16 | — | — | EP | disclosed |
| WO-2012059583-A1 | NOVEL APPLICATIONS OF INDOLOINDOLE AND INDOLOQUINOLINE DYES | BIOSYNTH AG (CH) | 2012-05-10 | — | — | WO | disclosed |